acesulfame potassium

Small moleculeexperimental

Acesulfame potassium, also known as acesulfame K or Ace K, is a synthetic calorie-free sugar substitute often marketed under the trade names Sunett and Sweet One. In the European Union, it is known under the E number E950. It was discovered accidentally in 1967 by German chemist Karl Clauss at Hoechst AG. Acesulfame potassium is the potassium salt of 6-methyl-1,2,3-oxathiazine-4(3H)-one 2,2-dioxide. It is a white crystalline powder with molecular formula C4H4KNO4S and a molecular weight of 201.24 g/mol. — Wikipedia

Clinical trial activity

4 trials · 3 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0

Earliest trial started Mar 1, 2015 (NCT02891525)

Timeline

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Chemistry & pharmacology

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SMILES

CC1=CC(=O)NS(=O)(=O)O1
Mol. weight
163.15 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 3,4-dihydro-6-methyl-1,2,3-oxathiazin-4-one-2,2-dioxide potassium salt
  • acesulfame
  • acesulfame
  • acesulfame calcium
  • acesulfame k
  • acesulfame-k
  • acesulfame-k
  • acesulfame potassium
  • acesulfame potassium
  • acesulfame potassium
  • acesulfame sodium
  • acesulfam-k
  • acetosulfam
  • acetosulfame
  • acetosulfame calcium
  • acetosulfam potassium
  • acetosulfam, potassium salt
  • acetosulfam, sodium salt
  • e950
  • e950

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT04578431N/ANov 1, 2020Aarhus University
NCT03954418N/AJun 1, 2019Aarhus University
NCT03232008N/ASep 1, 2015University of London
NCT02891525N/AMar 1, 2015Katholieke Universiteit Leuven
Showing 4 of 4 trials
Page 1 / 1

Organizations

Research & Development (3)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Aarhus UniversityAcademic/Hospital2212019
Katholieke Universiteit LeuvenAcademic/Hospital1112015
University of LondonAcademic/Hospital1112015
3 organizations
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