tyropanoate sodium

Trade name: bilopaque

Small moleculeapproved

Approved

Oct 24, 1969

Tyropanoic acid and its salt sodium tyropanoate are radiocontrast agents used in cholecystography. Trade names include Bilopaque, Lumopaque, Tyropaque, and Bilopac. This molecule contains three heavy iodine atoms which obstruct X-rays in the same way as the calcium in bones to produce a visible image. After injection it is rapidly excreted into the bile. — Wikipedia

Clinical trial activity

0 trials · 0 clinical orgs · 1 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0

Timeline

1960s

  1. Oct 24, 1969

    General Electric — Earliest FDA Approval

  2. Oct 24, 1969

    General Electric — NDA Secondary Org

  3. Oct 24, 1969

    General Electric — NDA Organization

Indications

Mechanism of action

Approval history

  • approvedOct 24, 1969

Chemistry & pharmacology

Loading structure…

SMILES

CCCC(=O)Nc1c(I)cc(I)c(CC(CC)C(=O)[O-])c1I.[Na+]
Mol. weight
663.01 g/mol
Lipinski Ro5
1 violation(s)
Rule of 3
No
Chirality
Racemic Mixture
Inorganic
No
Polymer
No
Delivery
Oral
Availability
Discontinued

Oral

Yes

Parenteral

No

Topical

No

Sources

Also known as

  • bilopaque
  • bilopaque
  • bilopaque
  • sodium tyropanoate
  • sodium tyropanoate
  • tyropanoate sodium
  • tyropanoate sodium
  • tyropanoate sodium
  • tyropanoate sodium
  • tyropanoate sodium
  • win-88512
  • win-88512
  • win-8851-2
  • win-8851-2

Organizations

Marketing (2)

OrganizationOrg typeRelationshipDate
General ElectricFor profitNDA2Oct 24, 1969
General ElectricFor profitNDAOct 24, 1969