trichlorethylene
Trade name: Trilene
Small moleculeapproved
Approved
Jul 1, 1941
Trichloroethylene (or TCE), a synthetic chemical that does not occur naturally in the environment. TCE is used to make chemicals. Additionally, it is used for spot removal in dry cleaning operations. TCE is the most common organic contaminant in groundwater. It was revealed that the compound was a human carcinogen that caused liver cancer, kidney cancer, and non-Hodgkin's lymphoma (NHL). — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 1 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Timeline
1940s
- Jul 1, 1941
Earliest FDA Approval
Indications
Approved for
Mechanism of action
GUCA2B agonist
Approval history
- approvedJul 1, 1941
Chemistry & pharmacology
Loading structure…
SMILES
ClC=C(Cl)Cl- Mol. weight
- 131.388 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- Yes
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaTrichloroethylene ↗
- NCATS290YE8AR51 ↗
- ChEMBLCHEMBL279816 ↗
Also known as
- 1,1,2-trichloroethylene
- chlorilen
- chlorylen
- chlorylen
- ethylene trichloride
- trichloroethene
- trichloroethylene
- trichloroethylene
- trichloroethylene
- trichloroethylene
- trichloroethylene
- trichloroethylene
- trilene
- trilene
- trilene
Organizations
Marketing (1)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Ayerst, McKenna and Harrison | For profit | NDA | — |