rose bengal sodium i-131

Trade name: Robengatope

Small moleculeapprovedImaging agent

Approved

Nov 23, 1971

Clinical trial activity

2 trials · 2 clinical orgs · 2 marketing orgs

Phase 1
2
Phase 2
1
Phase 3
0
Phase 4
0

Earliest trial started Jan 24, 2013 (NCT01760499)

Timeline

1970s

  1. Nov 23, 1971

    Bracco — Earliest FDA Approval

  2. Nov 23, 1971

    Bracco — NDA Secondary Org

  3. Nov 23, 1971

    Bracco — NDA Organization

2010s

  1. Jan 1, 2013

    Earliest Phase 1 Sponsor(trial)

Indications

Mechanism of action

  • Unspecified targetRadiopharmaceutical

    Radiopharmaceutical

Approval history

  • approvedPriority reviewNov 23, 1971

Chemistry & pharmacology

Loading structure…

SMILES

OC(=O)C1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1C2=C3C=C([131I])C(=O)C([131I])=C3OC4=C2C=C([131I])C(O)=C4[131I]
Mol. weight
989.679 g/mol
Imaging
131-iodine

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • pv-10
  • pv-10
  • robengatope
  • robengatope
  • robengatope
  • robengatope i-131
  • rose bengal (131i) sodium
  • rose bengal (131i) sodium
  • rose bengal sodium (131i)
  • rose bengal sodium (131i)
  • rose bengal sodium i 131
  • rose bengal sodium i 131
  • rose bengal sodium i-131
  • rose bengal sodium i-131
  • rose bengal sodium i-131
  • sodium rose bengal (131i)

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT02557321Phase 1/Phase 2 (Phase 2)Oct 1, 2015Provectus Biopharmaceuticals, Inc.
NCT01760499Phase 1Jan 24, 2013Provectus Biopharmaceuticals, Inc., University of South Florida
Showing 2 of 2 trials
Page 1 / 1

Organizations

Research & Development (2)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Provectus Biopharmaceuticals, Inc.For profit2122013
University of South FloridaAcademic/Hospital1112013
2 organizations
Page 1 / 1

Marketing (3)

OrganizationOrg typeRelationshipDate
BraccoFor profitNDA2Nov 23, 1971
BraccoFor profitNDANov 23, 1971
SorinFor profitNDA2