iotrolan

Trade name: osmovist

Small moleculeapproved

Approved

Jun 1, 1984

Iotrol, a nonionic dimeric, intrathecal contrast medium for myelography. This agent does not exhibit any cytotoxic effect on human healthy nucleus pulposus (NP) cells. — NCATS

Clinical trial activity

0 trials · 0 clinical orgs · 2 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0

Timeline

1980s

  1. Jun 1, 1984

    Earliest FDA Approval

  2. Nov 8, 1984

    Schering — First NDA Organization

  3. Nov 8, 1984

    Schering — NDA Organization

Indications

Mechanism of action

Approval history

  • approvedJun 1, 1984

Chemistry & pharmacology

Loading structure…

SMILES

CN(C(=O)CC(=O)N(C)C1=C(I)C(C(=O)NC(CO)C(O)CO)=C(I)C(C(=O)NC(CO)C(O)CO)=C1I)C2=C(I)C(C(=O)NC(CO)C(O)CO)=C(I)C(C(=O)NC(CO)C(O)CO)=C2I
Mol. weight
1626.2332 g/mol
Chirality
Racemic Mixture
Inorganic
No
Polymer
No
Delivery
Parenteral
Availability
Discontinued

Oral

No

Parenteral

Yes

Topical

No

Sources

Also known as

  • 1,3-benzenedicarboxamide, 5,5'-((1,3-dioxo-1,3-propanediyl)bis(methylimino))bis(n,n'-bis(2,3-dihydroxy-1-(hydroxymethyl)propyl))-2,4,6-triiodo-
  • berlex brand of iotrolan
  • dl 3117
  • dl 3-117
  • dl-3-117
  • iotrol
  • iotrol
  • iotrol
  • iotrol
  • iotrolan
  • iotrolan
  • iotrolan
  • iotrolan
  • iotrolan
  • iotrolan
  • iotrolan
  • iotrolan
  • iotrovist
  • isovist
  • isovist
  • isovist 300
  • osmovist
  • osmovist
  • osmovist
  • osmovist
  • osmovist 190
  • osmovist 190
  • osmovist 240
  • osmovist 240
  • schering brand of iotrolan
  • zk-39482
  • zk-39482

Organizations

Marketing (2)

OrganizationOrg typeRelationshipDate
BayerFor profitNDA2
ScheringFor profitNDANov 8, 1984