hexafluorenium

Trade name: mylaxen

Small moleculeapproved

Thiram is a pesticide, It is used as a fungicide, ectoparasiticide to prevent fungal diseases in seed and crops. It is also used as an animal repellent to protect fruit trees and ornamentals from damage by rabbits, rodents and deer. Thiram belongs to the ethylene bisdithiocarbamate (EBDC) chemical class. It is available as dust, flowable, wettable powder, water dispersible granules, and water suspension formulations and in mixtures with other fungicides. Thiram has been used in the treatment of human scabies, as a sun screen and as a bactericide applied directly to the skin or incorporated into soap. Thiram is a skin sensitizer. It is moderately toxic by ingestion, but it is highly toxic if inhaled. Acute exposure in humans may cause headaches, dizziness, fatigue, nausea, diarrhea and other gastrointestinal complaints. In rats and mice, large doses of thiram produced muscle incoordination, hyperactivity followed by inactivity, loss of muscular tone, labored breathing, convulsions and death. — NCATS

Clinical trial activity

0 trials · 0 clinical orgs · 2 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0

Timeline

1950s

  1. Jun 1, 1959

    Irwin Neisler, & Company — First NDA Organization

  2. Jun 1, 1959

    Irwin Neisler, & Company — NDA Organization

Indications

Approved for

Mechanism of action

Approval history

  • approved

Chemistry & pharmacology

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SMILES

C[N+](C)(CCCCCC[N+](C)(C)C1c2ccccc2-c2ccccc21)C1c2ccccc2-c2ccccc21
Mol. weight
502.75 g/mol
Lipinski Ro5
2 violation(s)
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No
Delivery
Parenteral
Availability
Discontinued

Oral

No

Parenteral

Yes

Topical

No

Sources

Also known as

  • hexafluorenium
  • hexafluorenium
  • hexafluorenium
  • hexafluorenium
  • hexafluorenium
  • hexafluorenium
  • hexafluorenium
  • hexafluorenium bromide
  • hexafluorenium bromide
  • hexafluorenium bromide
  • hexafluorenium bromide
  • hexafluorenium bromide
  • hexafluorenium bromide
  • hexafluorenium bromide
  • hexafluorenium cation
  • hexafluorenium cation
  • hexafluorenium dibromide
  • hexafluorenium dibromide salt
  • hexafluorenium ion
  • hexafluorenium ion
  • hexaflurone bromide
  • hexaflurone bromide
  • hexafluronium
  • hexafluronium
  • hexafluronium
  • hexafluronium
  • hexafluronium
  • hexafluronium bromide
  • hexafluronium bromide
  • hexafluronium bromide
  • hexafluronium bromide
  • hexamethylenebis(fluoren-9-yldimethylammonium)
  • hexamethylenebis(fluoren-9-yldimethylammonium)
  • hexamethylenebis(fluoren-9-yldimethylammonium) dibromide
  • mylaxen
  • mylaxen
  • mylaxen
  • mylaxen

Organizations

Marketing (2)

OrganizationOrg typeRelationshipDate
Irwin Neisler, & CompanyFor profitNDAJun 1, 1959
MedpointeFor profitNDA2