hexafluorenium
Trade name: mylaxen
Thiram is a pesticide, It is used as a fungicide, ectoparasiticide to prevent fungal diseases in seed and crops. It is also used as an animal repellent to protect fruit trees and ornamentals from damage by rabbits, rodents and deer. Thiram belongs to the ethylene bisdithiocarbamate (EBDC) chemical class. It is available as dust, flowable, wettable powder, water dispersible granules, and water suspension formulations and in mixtures with other fungicides. Thiram has been used in the treatment of human scabies, as a sun screen and as a bactericide applied directly to the skin or incorporated into soap. Thiram is a skin sensitizer. It is moderately toxic by ingestion, but it is highly toxic if inhaled. Acute exposure in humans may cause headaches, dizziness, fatigue, nausea, diarrhea and other gastrointestinal complaints. In rats and mice, large doses of thiram produced muscle incoordination, hyperactivity followed by inactivity, loss of muscular tone, labored breathing, convulsions and death. — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 2 marketing orgs
Timeline
1950s
- Jun 1, 1959
Irwin Neisler, & Company — First NDA Organization
- Jun 1, 1959
Irwin Neisler, & Company — NDA Organization
Indications
Approved for
Mechanism of action
- AcetylcholinesteraseINHIBITOR
ACHE inhibitor
Approval history
- approved—
Chemistry & pharmacology
SMILES
C[N+](C)(CCCCCC[N+](C)(C)C1c2ccccc2-c2ccccc21)C1c2ccccc2-c2ccccc21- Mol. weight
- 502.75 g/mol
- Lipinski Ro5
- 2 violation(s)
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
- Delivery
- Parenteral
- Availability
- Discontinued
Oral
No
Parenteral
Yes
Topical
No
Sources
- ChEMBLCHEMBL1201349 ↗
- WikipediaHexafluronium bromide ↗
- NCATS0D771IS0FH ↗
- ChEMBLCHEMBL120563 ↗
- ChEMBLCHEMBL1200933 ↗
- NCATS55W5L6G81R ↗
Also known as
- hexafluorenium
- hexafluorenium
- hexafluorenium
- hexafluorenium
- hexafluorenium
- hexafluorenium
- hexafluorenium
- hexafluorenium bromide
- hexafluorenium bromide
- hexafluorenium bromide
- hexafluorenium bromide
- hexafluorenium bromide
- hexafluorenium bromide
- hexafluorenium bromide
- hexafluorenium cation
- hexafluorenium cation
- hexafluorenium dibromide
- hexafluorenium dibromide salt
- hexafluorenium ion
- hexafluorenium ion
- hexaflurone bromide
- hexaflurone bromide
- hexafluronium
- hexafluronium
- hexafluronium
- hexafluronium
- hexafluronium
- hexafluronium bromide
- hexafluronium bromide
- hexafluronium bromide
- hexafluronium bromide
- hexamethylenebis(fluoren-9-yldimethylammonium)
- hexamethylenebis(fluoren-9-yldimethylammonium)
- hexamethylenebis(fluoren-9-yldimethylammonium) dibromide
- mylaxen
- mylaxen
- mylaxen
- mylaxen
Organizations
Marketing (2)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Irwin Neisler, & Company | For profit | NDA | Jun 1, 1959 |
| Medpointe | For profit | NDA2 | — |