haloprogin
Trade name: halotex
Approved
Aug 6, 1971
Haloprogin is an active synthetic antifungal and antimonilial agent that was effective in the treatment of superficial fungal and monilial infections of the skin. Because of these two basic therapeutic effects, haloprogin was especially useful in the treatment of infections when the identity of the specific causative organism had not been established or is being determined. Studies in-vitro demonstrated antifungal, antimonilial and antibacterial activity. It was shown to demonstrate marked in-vitro activity against Staphylococcus and Streptococcus. Haloprogin is no longer available in the US. — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 1 marketing orgs
Timeline
Indications
Mechanism of action
- Cell membraneINHIBITOR
Cell membrane inhibitor
Disrupts cell membrane
Approval history
- approvedPriority reviewAug 6, 1971
Chemistry & pharmacology
SMILES
ClC1=CC(Cl)=C(OCC#CI)C=C1Cl- Mol. weight
- 361.391 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
- Delivery
- Topical
- Availability
- Discontinued
Oral
No
Parenteral
No
Topical
Yes
Sources
- WikipediaHaloprogin ↗
- NCATSAIU7053OWL ↗
- ChEMBLCHEMBL1289 ↗
Also known as
- haloprogin
- haloprogin
- haloprogin
- haloprogin
- haloprogin
- haloprogin
- haloprogin
- haloprogin
- haloprogin
- haloprogin
- haloprogina
- haloprogina
- haloprogine
- haloprogine
- haloprogine
- haloprogine
- haloprogine
- haloproginum
- haloproginum
- halotex
- halotex
- halotex
- halotex
- m-1028
- m-1028
- mycanden
- mycanden
- mycilan
- théraplix brand of haloprogin
- westwood squibb brand of haloprogin
Organizations
Marketing (1)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Squibb | For profit | NDA | Aug 6, 1971 |