ethoxzolamide

Trade name: ethamide

Small moleculeapproved

Approved

Oct 12, 1966

Ethoxzolamide is a carbonic anhydrase I inhibitor. It is used in the treatment of glaucoma and duodenal ulcers, and as a diuretic. Ethoxzolamide was marketed under trade name Cadrase, but is now discontinued. — NCATS

Clinical trial activity

0 trials · 0 clinical orgs · 2 marketing orgs

Phase 1

Phase 2

Phase 3

Phase 4

Timeline

1960s

Oct 12, 1966
Allergan — Earliest FDA Approval
Oct 12, 1966
Allergan — NDA Secondary Org
Oct 12, 1966
Allergan — NDA Organization

Indications

Approved for

Approval history

approvedOct 12, 1966

Chemistry & pharmacology

Loading structure…

SMILES

CCOC1=CC2=C(C=C1)N=C(S2)S(N)(=O)=O

Mol. weight: 258.317 g/mol
Lipinski Ro5: Pass
Rule of 3: No
Chirality: Achiral Molecule
Inorganic: No
Polymer: No
Availability: Discontinued

Oral

Parenteral

Topical

Sources

Also known as

6-ethoxy-1,3-benzothiazole-2-sulfonamide
6-ethoxy-1,3-benzothiazole-2-sulfonamide
cardrase
cardrase
cardrase
ethamide
ethamide
ethamide
ethoxazolamide
ethoxazolamide
ethoxyzolamide
ethoxyzolamide
ethoxyzolamide
ethoxzolamide
ethoxzolamide
ethoxzolamide
ethoxzolamide
ethoxzolamide
ethoxzolamide
ethoxzolamide
ethoxzolamide
ethoxzolamide
ethoxzolamide
etoxzolamide

Organizations

Marketing (3)

Organization	Org type	Relationship	Date
Allergan	For profit	NDA2	Oct 12, 1966
Allergan	For profit	NDA	Oct 12, 1966
Pharmacia & Upjohn	For profit	NDA2	—