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amylocaine

Trade name: stovaine

Small moleculemarketed

Approved

Jul 1, 1909

Amylocaine (trade name Stovaine) is a local anesthetic, that was widely used for spinal anesthesia in Caesarean section. The dose used would produce anesthesia for up to 1 h. Reports of the use of spinal analgesia for abdominal and perineal surgery in infants are found from several centers during the first half of the twentieth century. However, this agent often fails to provide good maternal sensory block and currently, Amylocaine has been replaced with new anesthetics. — NCATS

Clinical trial activity

0 trials · 0 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0

Timeline

1900s

  1. Jul 1, 1909

    Evidence of US Marketing

Indications

Approved for

Mechanism of action

Approval history

  • approvedJul 1, 1909

Chemistry & pharmacology

Loading structure…

SMILES

CCC(C)(CN(C)C)OC(=O)C1=CC=CC=C1
Mol. weight
235.322 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Racemic Mixture
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 1-(dimethylamino)-2-methyl-2-butanol benzoate
  • 1-(dimetylaminometyl)-1-metylpropyl benzoate
  • amyleine
  • amyleine
  • amyléine
  • amyléine
  • amyleine hcl
  • amyleine hydrochloride
  • amylocaine
  • amylocaine
  • amylocaine
  • amylocaine
  • amylocaine
  • amylocaine
  • amylocaine
  • amylocaine
  • amylocaine hcl
  • amylocaine hydrochloride
  • amylocaine hydrochloride
  • dolodent
  • stovaine
  • stovaine
  • stovaine
  • stovaine
  • stovaine