salicin
Small moleculeexperimental
The most well known component of willow bark extract is salicin, it is a prodrug, which is gradually transported to the lower part of the intestine, hydrolyzed to saligenin by intestinal bacteria, and converted to salicylic acid after absorption. Salicin possesses an analgesic, anti-inflammatory, and antipyretic properties. Salicin suppressed the activation of MAPKs and NF-κB signaling pathways and thus maybe might be a potential therapeutic agent against inflammatory diseases. — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Chemistry & pharmacology
Loading structure…
SMILES
OC[C@H]1O[C@@H](OC2=C(CO)C=CC=C2)[C@H](O)[C@@H](O)[C@@H]1O- Mol. weight
- 286.2778 g/mol
Oral
No
Parenteral
No
Topical
No
Sources
- NCATS4649620TBZ ↗
Also known as
- salicin
- salicin
- salicin
- salicyl alcohol glucoside