cinchophen

Small moleculeexperimental

Cinchophen, phenylcinchoninic acid, seems to have been discovered in 1887 by Doebner and Gieseke and to have been introduced into medicine under the trade name of atophan in 1908 by Nicolaier and Dohrn. Since that time it has been used extensively for gout as well as for other forms of arthritis and for the relief of pain of all types. Use of Cinchophen in humans ceased in the 1930s due to the discovery that it can cause serious liver damage. — NCATS

Clinical trial activity

0 trials · 0 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0

Indications

Approved for

Chemistry & pharmacology

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SMILES

OC(=O)C1=CC(=NC2=C1C=CC=C2)C3=CC=CC=C3
Mol. weight
249.264 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • aciphenochinoline
  • aciphenochinolinium
  • aciphenochinolium
  • atofan
  • cincain
  • cinchophen
  • cinchophen
  • cinchophen
  • cinchophen
  • cinchophen
  • cinchophen
  • cinchophene
  • cinchophenic acid
  • cinconal
  • cincophen
  • phenoquin
  • phenylcinchoninic acid
  • phenylcinchoninic acid
  • phenylcinchoninic acid
  • phenylcinchoninic acid
  • phenylcinchoninic acid
  • quinofen
  • quinophan
  • quinophen