gallate
Gallic acid is a polyphenol found in a variety of foods and herbs. Several studies have shown thta gallic acid has neuroprotective and anti-oxidant properties and can be a promising candidate for the treatment of cancer, cardiovascular diseases, neurodegenerative disorders, fatty liver disease and many others. Gallic acid acts by protecting cells against oxidative damage caused by reactive species often encountered in biological systems including, hydroxyl, superoxide and peroxyl and the non-radicals, hydrogen peroxide and hypochlorous acid. However, its ability to induce apoptosis, is mainly associated with its prooxidant, rather than antioxidant behavior. — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Chemistry & pharmacology
SMILES
OC(=O)C1=CC(O)=C(O)C(O)=C1- Mol. weight
- 170.1195 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- NCATS632XD903SP ↗
- ChEMBLCHEMBL288114 ↗
Also known as
- gallate
- gallate
- gallic acid
- gallic acid
- gallic acid