formaldehyde
Small moleculeexperimental
Formaldehyde is a naturally occurring organic compound, and an important industrial precursor to many other materials and organic compounds. Formaldehyde solution (formalin) is used as a disinfectant. Formaldehyde vapors are toxic, upon entry formaldehyde reacts readily with macromolecules, including DNA to form DNA-protein and DNA-DNA cross-links. — NCATS
Clinical trial activity
2 trials · 3 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Apr 1, 2009 (NCT00723918)
Timeline
2000s
- Jan 1, 2009
Earliest Phase 2 Sponsor(trial)
Indications
Approved for
Mechanism of action
- Unspecified targetCROSS-LINKING AGENT
cross-linking agent
Chemistry & pharmacology
Loading structure…
SMILES
C=O- Mol. weight
- 30.026 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- Yes
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaFormaldehyde ↗
- NCATS1HG84L3525 ↗
- ChEMBLCHEMBL1255 ↗
Also known as
- dowling's
- e240
- e240
- formaldehyde
- formaldehyde
- formaldehyde
- formaldehyde
- formaldehyde
- formaldehyde
- formaldehyde
- formaldehyde solution
- formaldehyde solution
- formalin
- formalin
- formalin
- formalin
- formol
- formol
- formol
- formol
- formol
- formol
- methanal
- methanal
- methanone
- methanone
- methyl aldehyde
- methyl aldehyde
- methylene oxide
- methylene oxide
- oxomethane
- oxomethane
- oxomethylene
- oxomethylene
- oxymethylene
- oxymethylene
- veracur
- veracur
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT02629315 | N/A | May 10, 2012 | Instituto do Cancer do Estado de São Paulo |
| NCT00723918 | Phase 2 | Apr 1, 2009 | National Institute of Neurological Disorders and Stroke (NINDS), Washington University in St. Louis |
Showing 2 of 2 trials
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Organizations
Research & Development (3)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Instituto do Cancer do Estado de São Paulo | Academic/Hospital | 1 | 1 | 1 | 2012 |
| National Institute of Neurological Disorders and Stroke (NINDS) | Government | 1 | 0 | 1 | 2009 |
| Washington University in St. Louis | Academic/Hospital | 1 | 1 | 1 | 2009 |
3 organizations
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