progestoral

Small moleculeexperimental

Ethisterone is a metabolite of danazol. Ethisterone is a progestogen hormone. The first orally active progestin, Ethisterone (brand names Pranone, Progestoral, Lutocylol, Proluton C), also known as 17α-ethinyltestosterone, pregneninolone, or anhydrohydroxyprogesterone, is a steroidal progestin with androgenic activity which is derived from testosterone and was introduced for medical use in 1939. Ethisterone is indicated for progesterone supplementation or replacement as part of an Assisted Reproductive Technology (ART) treatment for infertile women with progesterone deficiency and for the treatment of secondary amenorrhea. Also used as a female contraceptive. — NCATS

Clinical trial activity

0 trials · 0 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0

Indications

Chemistry & pharmacology

Loading structure…

SMILES

C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@]2(O)C#C
Mol. weight
312.4458 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • aethisteron
  • anhydrohydroxyprogesterone
  • anhydrohydroxyprogesterone
  • anhydrohydroxyprogesterone
  • anhydroxyprogesterone
  • ethinone
  • ethinyltestosterone
  • ethisterone
  • ethisterone
  • ethisterone
  • ethisterone
  • ethisterone
  • ethisterone
  • ethynyltestosterone
  • formula 405
  • formula 405
  • nugestoral
  • ora-lutin
  • ora-lutin
  • pranone
  • pranone
  • pregneninolone
  • pregneninolone
  • pregneninolone
  • progestoral
  • syngestrotabs
  • syngestrotabs
  • trosinone
  • trosinone