oxycholin
Small moleculeexperimental
Dehydrocholic acid is manufactured from cholic acid by oxidation. The main use of dehydrocholic acid is as a digestive aid in the dietary supplement industry. It is typically formulated with enzymes like papain and pancreatin. It has a stimulating effect on the secretion of bile by the liver (choleretic); improves absorption of essential food materials in states associated with deficient bile formation. — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Indications
Approved for
Mechanism of action
- Unspecified targetOTHER
Unknown
Dehydrocholic acid is a synthetic bile acid, manufactured by the oxidation of cholic acid. It acts as a hydrocholeretic, increasing bile output to clear increased bile acid load.
Chemistry & pharmacology
Loading structure…
SMILES
C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@H]3[C@H](CC(=O)[C@]12C)[C@@]4(C)CCC(=O)C[C@H]4CC3=O- Mol. weight
- 402.5238 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- NCATSNH5000009I ↗
- ChEMBLCHEMBL514446 ↗
Also known as
- cholepatin
- decholin
- decholin
- decholin
- dehydrocholate
- dehydrocholate
- dehydrocholic acid
- dehydrocholic acid
- dehydrocholic acid
- dehydrocholic acid
- dehydrocholic acid
- dehydrocholic acid
- dehydrocholic acid
- dehydrocholic acid
- dehystolin
- dilabil
- dilabil
- ketocholanic acid
- oxycholin
- procholon
- procholon