chlorquinaldol
Chlorquinaldol is a halogenated hydroxyquinoline with properties similar to those of clioquinol. It is mainly applied topically in infected skin conditions and in vaginal infections. The product is applied for local treatment of cortico-sensitive dermatosis with moderately manifested superinfection, acute and subacute eczema, dermatitis, pyodermia, intertrigo, infected wounds, dermatomycosis, pemphigus in newborn. Chlorquinaldol is also used as antiseptic, fungistat, or deodorant. Chlorquinaldol is not commercially available in the U.S. but is used in other countries principally as an amebicide for nonspecific diarrheas and gynecologic infections. It is known most commonly under the proprietary name of Sterosan. Other trade names include Cynotherax, Gyno-Sterosan, Saprosan, Siogeno, Siosteran, Slosteran and Steroxin. — NCATS
Clinical trial activity
1 trials · 2 clinical orgs · 0 marketing orgs
Earliest trial started Jul 1, 2010 (NCT01153958)
Timeline
No events for the selected filters.
Indications
Studied for
Mechanism of action
- Unspecified targetOTHER
Unknown
Local anti-infective agent used for skin, gastrointestinal, and vaginal infections with fungi, protozoa, and certain bacteria.
Chemistry & pharmacology
SMILES
CC1=NC2=C(O)C(Cl)=CC(Cl)=C2C=C1- Mol. weight
- 228.075 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaChlorquinaldol ↗
- NCATSD6VHC87LLS ↗
- ChEMBLCHEMBL224325 ↗
Also known as
- chloquinan
- chlorchinaldin
- chlorchinaldol
- chlorguinaldon
- chlorquinaldol
- chlorquinaldol
- chlorquinaldol
- chlorquinaldol
- chlorquinaldol
- chlorquinaldol
- chlorquinaldol
- clorquinaldol
- clorquinaldol
- steroxin
- steroxin
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01153958 | Phase 4 | Jul 1, 2010 | Merck KGaA, Merck Serono |
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Merck KGaA | For profit | 1 | 1 | 1 | 2010 |
| Merck Serono | For profit | 1 | 0 | 1 | 2010 |