ectoine
Ectoine is a natural compound found in several species of bacteria. It is a compatible solute which serves as a protective substance by acting as an osmolyte and thus helps organisms survive extreme osmotic stress. Furthermore it was shown to protect DNA against ionizing and ultraviolet radiation serving as a radical scavenger. Ectoine is found in high concentrations in halophilic microorganisms and confers resistance towards salt and temperature stress. Ectoine was first identified in the microorganism Ectothiorhodospira halochloris, but has since been found in a wide range of Gram-negative and Gram-positive bacteria. Other species of bacteria in which ectoine was found include:Brevibacterium linens Halomonas elongata Marinococcus halophilus Pseudomonas stutzeri Halomonas titanicae Halorhodospira halophila Halomonas ventosae — Wikipedia
Clinical trial activity
1 trials · 2 clinical orgs · 0 marketing orgs
Earliest trial started Jun 11, 2017 (NCT03186755)
Timeline
No events for the selected filters.
Indications
Approved for
Studied for
Mechanism of action
- Unspecified targetUltraviolet filter
ultraviolet filter
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaEctoine ↗
Also known as
- 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid
- 4-pyrimidinecarboxylic acid, 1,4,5,6-tetrahydro-2-methyl-, (+)-
- ectoin
- ectoine
- ectoine
- ectoine
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03186755 | Phase 4 | Jun 11, 2017 | St. Justine's Hospital, University of Montreal |
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| St. Justine's Hospital | Academic/Hospital | 1 | 1 | 1 | 2017 |
| University of Montreal | Academic/Hospital | 1 | 0 | 1 | 2017 |