ectoine

Small moleculeexperimental

Ectoine is a natural compound found in several species of bacteria. It is a compatible solute which serves as a protective substance by acting as an osmolyte and thus helps organisms survive extreme osmotic stress. Furthermore it was shown to protect DNA against ionizing and ultraviolet radiation serving as a radical scavenger. Ectoine is found in high concentrations in halophilic microorganisms and confers resistance towards salt and temperature stress. Ectoine was first identified in the microorganism Ectothiorhodospira halochloris, but has since been found in a wide range of Gram-negative and Gram-positive bacteria. Other species of bacteria in which ectoine was found include:Brevibacterium linens Halomonas elongata Marinococcus halophilus Pseudomonas stutzeri Halomonas titanicae Halorhodospira halophila Halomonas ventosae — Wikipedia

Clinical trial activity

1 trials · 2 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
1

Earliest trial started Jun 11, 2017 (NCT03186755)

Timeline

No events for the selected filters.

Indications

Mechanism of action

  • Unspecified targetUltraviolet filter

    ultraviolet filter

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid
  • 4-pyrimidinecarboxylic acid, 1,4,5,6-tetrahydro-2-methyl-, (+)-
  • ectoin
  • ectoine
  • ectoine
  • ectoine

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT03186755Phase 4Jun 11, 2017St. Justine's Hospital, University of Montreal
Showing 1 of 1 trials
Page 1 / 1

Organizations

Research & Development (2)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
St. Justine's HospitalAcademic/Hospital1112017
University of MontrealAcademic/Hospital1012017
2 organizations
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