azd-4877

Small moleculeexperimental

Clinical trial activity

6 trials · 2 clinical orgs · 0 marketing orgs

Phase 1
5
Phase 2
1
Phase 3
0
Phase 4
0

Earliest trial started Sep 1, 2006 (NCT00389389)

Timeline

2000s

  1. Jan 1, 2006

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2008

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

Cc1ccc(C(=O)N(CCCN)C(c2nc3snc(C)c3c(=O)n2Cc2ccccc2)C(C)C)cc1
Mol. weight
503.67 g/mol
Lipinski Ro5
1 violation(s)
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • azd4877
  • azd4877
  • azd4877
  • azd 4877
  • azd-4877
  • azd-4877
  • n-(3-aminopropyl)-n-(1-(5-benzyl-3-methyl-4-oxo-(1,2)thiazolo(5,4-d)pyrimidin-6-yl)-2-methylpropyl)-4-methylbenzamide

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT00661609Phase 2May 1, 2008AstraZeneca, Temple University
NCT00613652Phase 1Jan 1, 2008AstraZeneca
NCT00486265Phase 1Jul 1, 2007AstraZeneca
NCT00471367Phase 1Apr 1, 2007AstraZeneca
NCT00460460Phase 1Mar 1, 2007AstraZeneca
NCT00389389Phase 1Sep 1, 2006AstraZeneca
Showing 6 of 6 trials
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Organizations

Research & Development (2)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
AstraZenecaFor profit6622006
Temple UniversityAcademic/Hospital1012008
2 organizations
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