azd-4818
Small moleculeexperimental
Clinical trial activity
2 trials · 3 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Jan 1, 2008 (NCT00687232)
Timeline
Indications
Mechanism of action
- C-C chemokine receptor type 1ANTAGONIST
CCR1 antagonist
Chemistry & pharmacology
Loading structure…
SMILES
CC(=O)Nc1ccc(O)cc1OC[C@@](C)(O)CNC1CCN(Cc2ccc(Cl)cc2)CC1- Mol. weight
- 461.99 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL2178570 ↗
Also known as
- azd4818
- azd4818
- azd4818
- azd-4818
- azd-4818
- azd-4818
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT00629239 | Phase 2 | Jan 1, 2008 | AstraZeneca, University of Groningen |
| NCT00687232 | Phase 1 | Jan 1, 2008 | AstraZeneca, Osaka Pharmacology Clinical Research Hospital |
Showing 2 of 2 trials
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Organizations
Research & Development (3)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| AstraZeneca | For profit | 2 | 2 | 2 | 2008 |
| Osaka Pharmacology Clinical Research Hospital | Academic/Hospital | 1 | 0 | 1 | 2008 |
| University of Groningen | Academic/Hospital | 1 | 0 | 1 | 2008 |
3 organizations
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