tetraprenylacetone
Trade name: teprenon
Small moleculeexperimental
Clinical trial activity
5 trials · 4 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
1
Phase 4
3
Earliest trial started Aug 1, 2005 (NCT00125736)
Timeline
2010s
- Jan 1, 2011
Earliest Phase 2 Sponsor(trial)
Indications
Approved for
Mechanism of action
- Unspecified targetUnclear
Unclear
Chemistry & pharmacology
Loading structure…
SMILES
CC(=CCC\C(=C\CC\C(=C\CC\C(=C/CCC(=O)C)\C)\C)\C)C.CC(=CCC\C(=C\CC\C(=C\CC\C(=C\CCC(=O)C)\C)\C)\C)C- Mol. weight
- 661.11 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3989432 ↗
- ChEMBLCHEMBL79686 ↗
- ChEMBLCHEMBL5314356 ↗
Also known as
- 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraen-2-one
- geranylgeranylacetone
- geranylgeranylacetone
- geranylgeranylacetone
- geranylgeranylacetone
- geranyl-geranyl-acetone
- geranylgeranylacetone, (e,e,e)-isomer
- geranylgeranylacetone, (z,e,e)-isomer
- selbex
- selbex
- selbex
- teprenon
- teprenone
- teprenone
- teprenone
- teprenone
- teprenone
- teprenone
- tetraprenylacetone
- tetraprenylacetone
- tetraprenylacetone
- tetraprenylacetone
- tetraprenylacetone
- tetraprenyl acetone
- tetraprenyl acetone
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01397448 | Phase 2/Phase 3 (Phase 3) | Jul 1, 2011 | Eisai |
| NCT01284647 | Phase 4 | Feb 1, 2011 | Changhai Hospital, Eisai |
| NCT01190657 | Phase 4 | May 1, 2010 | Eisai, Jiao Tong University |
| NCT01547559 | N/A | Jun 1, 2007 | Sun Yat-Sen University |
| NCT00125736 | Phase 4 | Aug 1, 2005 | Eisai |
Showing 5 of 5 trials
Page 1 / 1
Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Eisai | For profit | 4 | 3 | 2 | 2005 |
| Changhai Hospital | Academic/Hospital | 1 | 1 | 1 | 2011 |
| Jiao Tong University | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Sun Yat-Sen University | Academic/Hospital | 1 | 1 | 1 | 2007 |
4 organizations
Page 1 / 1