hydrastis canadensis
Goldenseal, also called orangeroot or yellow puccoon, is a perennial herb in the buttercup family Ranunculaceae, native to North America. It may be distinguished by its thick, yellow knotted rootstock. The stem is purplish and hairy above ground and yellow below ground where it connects to the yellow rhizome. Goldenseal reproduces both clonally through the rhizome and sexually, with clonal division more frequent than asexual reproduction. It takes between 4 and 5 years for a plant to reach sexual maturity, i.e. the point at which it produces flowers. Plants in the first stage, when the seed erupts and cotyledons emerge, can remain in this state one or more years. The second vegetative stage occurs during years two and three and is characterized by the development of a single leaf and absence of a well developed stem. Finally, the third stage is reproductive, at which point flowering and fruiting occurs. This last stage takes between 4 and 5 years to develop. — Wikipedia
Clinical trial activity
2 trials · 3 clinical orgs · 0 marketing orgs
Earliest trial started Oct 1, 2013 (NCT02345447)
Timeline
Indications
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaGoldenseal ↗
Also known as
- hydrastis canadensis
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05081583 | Early Phase 1 (Phase 1) | Sep 16, 2021 | National Center for Complementary and Integrative Health (NCCIH), Washington State University |
| NCT02345447 | Phase 3 | Oct 1, 2013 | University of Tuebingen |
Organizations
Research & Development (3)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| National Center for Complementary and Integrative Health (NCCIH) | Government | 1 | 0 | 1 | 2021 |
| University of Tuebingen | Academic/Hospital | 1 | 1 | 1 | 2013 |
| Washington State University | Academic/Hospital | 1 | 1 | 1 | 2021 |