neuregulin
Recombinant proteinexperimental
Neuregulins are a family of four structurally related proteins that are part of the EGF family of proteins. These proteins have been shown to have diverse functions in the development of the nervous system and play multiple essential roles in vertebrate embryogenesis including: cardiac development, Schwann cell and oligodendrocyte differentiation, some aspects of neuronal development, as well as the formation of neuromuscular synapses. — Wikipedia
Clinical trial activity
9 trials · 25 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
8
Phase 3
7
Phase 4
0
Earliest trial started Apr 1, 2010 (NCT01131637)
Timeline
Indications
Studied for
Mechanism of action
- Pro-neuregulin-1, membrane-bound isoformSupplementation
NRG1 supplementation
Chemistry & pharmacology
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaNeuregulin ↗
Also known as
- neuregulin
- neuregulin-1
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04468529 | Phase 3 | Dec 30, 2020 | Capital Medical University, Central South University, China Three Gorges University, Yichang, China, Dalian Medical University, Haikou People's Hospital, Hainan People's Hospital, Jiao Tong University, Jilin University, Jinan University, Luoyang Central Hospital, People's Liberation Army of China, Shandong Province Qianfoshan Hospital, Shandong University, Shanghai Putuo District Central Hospital, Shanxi cardiovascular hospital, Shanxi Medical University, Shengjing Hospital, Soochow University, Zensun, Zhengzhou University, Zhongshan Medical University |
| NCT03388593 | Phase 3 | Jul 23, 2018 | Chinese Academy of Medical Sciences, Zensun |
| NCT01541202 | Phase 3 | Feb 1, 2012 | Chinese Academy of Medical Sciences, Zensun |
| NCT01251406 | Phase 2 | Jan 1, 2012 | University of California, San Diego, University of Southern California, Zensun |
| NCT01439789 | Phase 3 | Jun 1, 2011 | Chinese Academy of Medical Sciences, Zensun |
| NCT01439893 | Phase 3 | Jun 1, 2011 | Chinese Academy of Medical Sciences, Zensun |
| NCT01258387 | Phase 1 | Dec 1, 2010 | Acorda Therapeutics |
| NCT01214096 | Phase 3 | Jul 1, 2010 | Chinese Academy of Medical Sciences, Zensun |
| NCT01131637 | Phase 3 | Apr 1, 2010 | Chinese Academy of Medical Sciences, Zensun |
Showing 9 of 9 trials
Page 1 / 1
Organizations
Research & Development (25)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Zensun | For profit | 8 | 8 | 2 | 2010 |
| Chinese Academy of Medical Sciences | Academic/Hospital | 6 | 0 | 1 | 2010 |
| Acorda Therapeutics | For profit | 1 | 1 | 1 | 2010 |
| Capital Medical University | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Central South University | Academic/Hospital | 1 | 0 | 1 | 2020 |
| China Three Gorges University, Yichang, China | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Dalian Medical University | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Haikou People's Hospital | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Hainan People's Hospital | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Jiao Tong University | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Jilin University | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Jinan University | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Luoyang Central Hospital | Academic/Hospital | 1 | 0 | 1 | 2020 |
| People's Liberation Army of China | Government | 1 | 0 | 1 | 2020 |
| Shandong Province Qianfoshan Hospital | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Shandong University | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Shanghai Putuo District Central Hospital | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Shanxi cardiovascular hospital | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Shanxi Medical University | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Shengjing Hospital | Academic/Hospital | 1 | 0 | 1 | 2020 |
25 organizations
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