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barasertib

Small moleculeexperimental

Clinical trial activity

14 trials · 9 clinical orgs · 0 marketing orgs

Phase 1
10
Phase 2
5
Phase 3
1
Phase 4
0

Earliest trial started May 1, 2005 (NCT00497731)

Timeline

2000s

  1. Jan 1, 2005

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2009

    Earliest Phase 2 Sponsor(trial)

Indications

Studied for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CCN(CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)[nH]n3)ncnc2c1)CCOP(=O)(O)O
Mol. weight
587.55 g/mol
Lipinski Ro5
1 violation(s)
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Prodrug

Sources

Also known as

  • 2-((3-((4-((5-(2-((3-fluorophenyl)amino)-2-oxoethyl)-1h-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)propyl)(ethyl)amino)ethyl dihydrogen phosphate
  • azd1152
  • azd1152
  • azd1152
  • azd 1152
  • azd-1152
  • azd-1152
  • azd-1152
  • azd2811
  • azd2811
  • barasertib
  • barasertib
  • barasertib
  • barasertib

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT04745689Phase 2Feb 23, 2021AstraZeneca
NCT04525391Phase 2Sep 18, 2020Samsung Medical Center, Sungkyunkwan University
NCT03366675Phase 2Dec 1, 2017AstraZeneca, Sungkyunkwan University
NCT03217838Phase 1/Phase 2 (Phase 2)Jul 31, 2017AstraZeneca, SCRI Development Innovations
NCT02579226Phase 1Oct 28, 2015AstraZeneca, SCRI Development Innovations
NCT01354392Phase 1/Phase 2 (Phase 2)Sep 1, 2011The Christie NHS Foundation Trust, University of Manchester, University of Oxford
NCT01019161Phase 1Nov 1, 2009AstraZeneca, The Christie NHS Foundation Trust
NCT00952588Phase 2/Phase 3 (Phase 3)Jul 1, 2009AstraZeneca, University of Texas at Houston
NCT00926731Phase 1Jun 1, 2009AstraZeneca, University of Texas at Houston
NCT00530699Phase 1Nov 1, 2007AstraZeneca
NCT00497679Phase 1Aug 1, 2006AstraZeneca, University of Oxford
NCT00338182Phase 1May 23, 2006AstraZeneca
NCT00497991Phase 1May 1, 2006AstraZeneca
NCT00497731Phase 1May 1, 2005AstraZeneca, University of Amsterdam
Showing 14 of 14 trials
Page 1 / 1

Organizations

Research & Development (9)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
AstraZenecaFor profit121132005
SCRI Development InnovationsFor profit2022015
Sungkyunkwan UniversityAcademic/Hospital2112017
The Christie NHS Foundation TrustAcademic/Hospital2022009
University of OxfordAcademic/Hospital2122006
University of Texas at HoustonAcademic/Hospital2022009
Samsung Medical CenterAcademic/Hospital1112020
University of AmsterdamAcademic/Hospital1012005
University of ManchesterAcademic/Hospital1012011
9 organizations
Page 1 / 1