combretastatin

Small moleculeexperimental

Combretastatin is a dihydrostilbenoid found in Combretum afrum. — Wikipedia

Clinical trial activity

1 trials · 2 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
1
Phase 4
0

Earliest trial started Aug 1, 2007 (NCT00507429)

Timeline

2000s

  1. Jan 1, 2007

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

COc1ccc(C[C@@H](O)c2cc(OC)c(OC)c(OC)c2)cc1O
Mol. weight
334.37 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 3-hydroxy-4-methoxy-alpha-(3,4,5-trimethoxyphenyl)benzeneethanol
  • combretastatin
  • combretastatin
  • combretastatin
  • combretastatin
  • nsc 348103
  • nsc-348103

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT00507429Phase 2/Phase 3 (Phase 3)Aug 1, 2007Mateon Therapeutics, Yale University
Showing 1 of 1 trials
Page 1 / 1

Organizations

Research & Development (2)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Mateon TherapeuticsFor profit1112007
Yale UniversityAcademic/Hospital1012007
2 organizations
Page 1 / 1