xylose
Approved
Mar 26, 1987
D-Xylose is a sugar originally isolated from wood. D-Xylose is a colorless to white crystalline powder that is used in food products such as breads, butter, and beverage industry as flavoring agent and sweetener. Specifically, D-Xylose is used to sweeten products intended for use by obese and diabetic customers because it is a non-caloric sweetener. It has a cool and refreshing taste and has the same sweetness as sucrose, and it is often used to sweeten a wide variety of foods and beverages such as spices, meat products, butter, etc. D-Xylose is a sugar widely used as diabetic sweetener in food and beverage. is a sugar first isolated from wood, and named for it. Xylose is classified as a monosaccharide of the aldopentose type, which means that it contains five carbon atoms and includes a formyl functional group. It is derived from hemicellulose, one of the main constituents of biomass. Like most sugars, it can adopt several structures depending on conditions. With its free carbonyl group, it is a reducing sugar. D-xylose absorbtion test has been used for diagnosis of intestinal malabsorption. — NCATS
Clinical trial activity
6 trials · 6 clinical orgs · 2 marketing orgs
Earliest trial started Oct 1, 2006 (NCT01957098)
Timeline
1980s
- Mar 26, 1987
Lyne Laboratories — Earliest FDA Approval
- Mar 26, 1987
Lyne Laboratories — NDA Secondary Org
- Mar 26, 1987
Lyne Laboratories — NDA Organization
Indications
Approved for
Mechanism of action
- Chitin synthase 1AGONIST
CHS1 agonist
Approval history
- approvedMar 26, 1987
Chemistry & pharmacology
SMILES
OC[C@@H](O)[C@H](O)[C@@H](O)C=O- Mol. weight
- 150.1299 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Delivery
- Oral
- Availability
- Discontinued
Oral
Yes
Parenteral
No
Topical
No
Sources
- WikipediaXylose ↗
- NCATSA1TA934AKO ↗
- ChEMBLCHEMBL502135 ↗
- ChEMBLCHEMBL1236821 ↗
Also known as
- wood sugar
- xylo-pfan
- xylo-pfan
- xylose
- xylose
- xylose
- xylose
- xylose
- xylose
- xylose
- xylose
- xylose
- xylose
- (+)-xylose
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05136092 | N/A | Nov 30, 2021 | Cornell University |
| NCT05008978 | N/A | Oct 25, 2019 | National University of Singapore |
| NCT02654301 | N/A | Jun 1, 2014 | Yonsei University |
| NCT01762566 | N/A | Jan 1, 2012 | University of Palermo |
| NCT01762579 | N/A | Jan 1, 2012 | University of Palermo |
| NCT01957098 | N/A | Oct 1, 2006 | Danisco, University of Copenhagen |
Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Palermo | Academic/Hospital | 2 | 2 | 1 | 2012 |
| Cornell University | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Danisco | For profit | 1 | 0 | 1 | 2006 |
| National University of Singapore | Academic/Hospital | 1 | 1 | 1 | 2019 |
| University of Copenhagen | Academic/Hospital | 1 | 1 | 1 | 2006 |
| Yonsei University | Academic/Hospital | 1 | 1 | 1 | 2014 |
Marketing (3)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Lyne Laboratories | For profit | NDA2 | Mar 26, 1987 |
| Lyne Laboratories | For profit | NDA | Mar 26, 1987 |
| Savage Labs | For profit | NDA2 | — |