xylose

Small moleculeapproved

Approved

Mar 26, 1987

D-Xylose is a sugar originally isolated from wood. D-Xylose is a colorless to white crystalline powder that is used in food products such as breads, butter, and beverage industry as flavoring agent and sweetener. Specifically, D-Xylose is used to sweeten products intended for use by obese and diabetic customers because it is a non-caloric sweetener. It has a cool and refreshing taste and has the same sweetness as sucrose, and it is often used to sweeten a wide variety of foods and beverages such as spices, meat products, butter, etc. D-Xylose is a sugar widely used as diabetic sweetener in food and beverage. is a sugar first isolated from wood, and named for it. Xylose is classified as a monosaccharide of the aldopentose type, which means that it contains five carbon atoms and includes a formyl functional group. It is derived from hemicellulose, one of the main constituents of biomass. Like most sugars, it can adopt several structures depending on conditions. With its free carbonyl group, it is a reducing sugar. D-xylose absorbtion test has been used for diagnosis of intestinal malabsorption. — NCATS

Clinical trial activity

6 trials · 6 clinical orgs · 2 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0

Earliest trial started Oct 1, 2006 (NCT01957098)

Timeline

1980s

  1. Mar 26, 1987

    Lyne Laboratories — Earliest FDA Approval

  2. Mar 26, 1987

    Lyne Laboratories — NDA Secondary Org

  3. Mar 26, 1987

    Lyne Laboratories — NDA Organization

Indications

Mechanism of action

Approval history

  • approvedMar 26, 1987

Chemistry & pharmacology

Loading structure…

SMILES

OC[C@@H](O)[C@H](O)[C@@H](O)C=O
Mol. weight
150.1299 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No
Delivery
Oral
Availability
Discontinued

Oral

Yes

Parenteral

No

Topical

No

Sources

Also known as

  • wood sugar
  • xylo-pfan
  • xylo-pfan
  • xylose
  • xylose
  • xylose
  • xylose
  • xylose
  • xylose
  • xylose
  • xylose
  • xylose
  • xylose
  • (+)-xylose

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT05136092N/ANov 30, 2021Cornell University
NCT05008978N/AOct 25, 2019National University of Singapore
NCT02654301N/AJun 1, 2014Yonsei University
NCT01762566N/AJan 1, 2012University of Palermo
NCT01762579N/AJan 1, 2012University of Palermo
NCT01957098N/AOct 1, 2006Danisco, University of Copenhagen
Showing 6 of 6 trials
Page 1 / 1

Organizations

Research & Development (6)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
University of PalermoAcademic/Hospital2212012
Cornell UniversityAcademic/Hospital1112021
DaniscoFor profit1012006
National University of SingaporeAcademic/Hospital1112019
University of CopenhagenAcademic/Hospital1112006
Yonsei UniversityAcademic/Hospital1112014
6 organizations
Page 1 / 1

Marketing (3)

OrganizationOrg typeRelationshipDate
Lyne LaboratoriesFor profitNDA2Mar 26, 1987
Lyne LaboratoriesFor profitNDAMar 26, 1987
Savage LabsFor profitNDA2