granulocytes

Cell therapyexperimental

Granulocytes are cells in the innate immune system characterized by the presence of specific granules in their cytoplasm. Such granules distinguish them from the various agranulocytes. All myeloblastic granulocytes are polymorphonuclear, that is, they have varying shapes (morphology) of the nucleus ; and are referred to as polymorphonuclear leukocytes. In common terms, polymorphonuclear granulocyte refers specifically to "neutrophil granulocytes", the most abundant of the granulocytes; the other types have varying morphology. Granulocytes are produced via granulopoiesis in the bone marrow. — Wikipedia

Clinical trial activity

5 trials · 20 clinical orgs · 0 marketing orgs

Phase 1
3
Phase 2
3
Phase 3
1
Phase 4
0

Earliest trial started Apr 1, 2008 (NCT00627393)

Timeline

2000s

  1. Jan 1, 2008

    Earliest Phase 3 Sponsor(trial)

  2. Jan 1, 2009

    Earliest Phase 1 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • granulocyte
  • granulocyte
  • granulocytes

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06240767Phase 1Nov 1, 2023Wuxi People's Hospital
NCT05425043N/ASep 14, 2021Children's Cancer and Leukaemia Group, University of Manchester
NCT04124666Phase 1/Phase 2 (Phase 2)Oct 1, 2019Huazhong University of Science and Technology
NCT00900497Phase 1/Phase 2 (Phase 2)Apr 1, 2009South Florida Bone Marrow/Stem Cell Transplant Institute
NCT00627393Phase 3Apr 1, 2008Cornell University, Emory University, Froedtert Memorial Lutheran Hospital, Harvard University, Johns Hopkins University, National Heart, Lung, and Blood Institute (NHLBI), New England Research Institutes, Puget Sound Blood Center, University of Iowa, University of Minnesota, University of Oklahoma, University of Pennsylvania, University of Pittsburgh, University of Washington, University of Wisconsin
Showing 5 of 5 trials
Page 1 / 1

Organizations

Research & Development (20)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Children's Cancer and Leukaemia GroupAcademic/Hospital1012021
Cornell UniversityAcademic/Hospital1012008
Emory UniversityAcademic/Hospital1012008
Froedtert Memorial Lutheran HospitalAcademic/Hospital1012008
Harvard UniversityAcademic/Hospital1012008
Huazhong University of Science and TechnologyAcademic/Hospital1112019
Johns Hopkins UniversityAcademic/Hospital1012008
National Heart, Lung, and Blood Institute (NHLBI)Government1012008
New England Research InstitutesFor profit1112008
Puget Sound Blood CenterAcademic/Hospital1012008
South Florida Bone Marrow/Stem Cell Transplant InstituteAcademic/Hospital1112009
University of IowaAcademic/Hospital1012008
University of ManchesterAcademic/Hospital1112021
University of MinnesotaAcademic/Hospital1012008
University of OklahomaAcademic/Hospital1012008
University of PennsylvaniaAcademic/Hospital1012008
University of PittsburghAcademic/Hospital1012008
University of WashingtonAcademic/Hospital1012008
University of WisconsinAcademic/Hospital1012008
Wuxi People's HospitalAcademic/Hospital1112023
20 organizations
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